Within the Steinbeis Foundation for Technology Development Stuttgart, one of the largest and most reputed Technology developing Organisations in Germany, the Steinbeis Centre for Biopolymer Analysis and Biomedical Mass Spectrometry, was founded in 2003 and located for 10 years at the University of Konstanz. The Laboratory is directed by Professor Michael Przybylski, Director of the Centre and Chair of the Analytical Chemistry Laboratory. After location in Rüsselsheim am Main in 2015, Professor Przybylski is presently the Director of the newly founded Centre. The laboratory has made numerous developments and inventions in biopolymer mass spectrometry, combined with protein- and peptide-chemical methods, tertiary structure analysis by protein-chemical modification and mass spectrometry, and the mass spectrometric determination of biopolymer recognition structures. The Steinbeis Centre has invented proteolytic-excision mass spectrometry for the elucidation of protein-ligand interaction structures, and peptide/protein epitopes, and has elucidated the structure of several membrane proteins, such as Lung Surfactant protein-C. The laboratory’s current research is focused on applications of mass spectrometry and peptide biochemistry to structure elucidation and and mechanism of neurodegenerative proteins; pathophysiological protein modification; vaccine chemistry; structure and epitope analysis of therapeutic antibodies; affinity-mass spectrometry of biopolymer interaction epitopes; mass spectrometric elucidation of oligomerisation/truncation pathways and structures of “misfolding”/aggregating proteins in neurodegenerative diseases.
WHERE WE ARE
Marktstraße 29 – 65428 Rüsselsheim am Main – Germany
Steinbeis Centre for Biopolymer Analysis and Biomedical Mass Spectrometry